Abstract: Using the common teaching mode in education and teaching, this paper compares the advantages and disadvantages of lecture-style and inquisitive teaching mode in earthquake popular science lectures, explores the specific process and practical operation method of their integration, and puts forward suggestions for optimization. It is concluded that the integrated application of lecture-style and inquisitive teaching mode in earthquake popular science lectures can not only accurately, systematically and comprehensively popularize the knowledge of earthquake disaster prevention and reduction to the audience, improve the efficiency of lectures, but also enable the audience to actively participate in exploration, actively think, construct concepts on their own, obtain more thorough and firm knowledge. To some extent, it solves the problem that the lecture full of lectures from beginning to end, lacking efficient interaction.